Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats
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چکیده
منابع مشابه
Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats
Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. Recent studies show that toll-like receptor 4 (TLR4) plays a critical role in promoting adaptive immune responses and have been shown to be associated with brain damage. The purpose of this stu...
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1Department of Neurology, School of Medicine, University of São Paulo (USP), São Paulo, Brazil, 2School of Medicine, Universidade da Cidade de São Paulo (UNICID), São Paulo, Brazil, 3Service of Interdisciplinary Neuromodulation, Institute of Psychiatry, Hospital das Clínicas HCFMUSP, University of São Paulo (USP), São Paulo, Brazil, 4Division of Psychology, Hospital das Clínicas HCFMUSP, Univer...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2016
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2016/4706915